Computational analysis of Strain Generated Potentials (SGPs) associated with transmission of acousto-elastic vibrations in normal and osteoporotic long bones

نویسندگان

  • R. Uklejewski
  • T. Czapski
چکیده

Electric potentials generated by mechanical strain of bones (SGPS: strain generated potentials) are one of the cofactors, which determine the adaptive remodelling processes in bone tissue [1,12,14]. The significance of the potentials SGPs in bone tissue biodynamics results from the electrosensivity of bone cells membranes via the Ca voltage-gated channels [7], Fig.1a. Bioelectric signals are also important in bone fractures healing: a strongly electronegative potential (the so-called fracture potential) appears immediately after a bone fracture, and during fracture healing it is normalized toward the normal bioelectric potential of a long bone [6], Fig.1b.

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تاریخ انتشار 2010